Publications by Nadine Saul
In 2022:
Saul N , Dhondt I, Kuokkanen M, Perola M, Verschuuren C, Wouters B, von Chrzanowski H , De Vos WH, Temmerman L, Luyten W, Zečić A, Loier T, Schmitz-Linneweber C , Braeckman BP.Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study. Zhang X, Saul N , Lieke T, Chen Y, Wu M, Pan B, Steinberg CEW.Dissolved organic matter modulates the toxicity of persistent free radicals on the nematode Caenorhabditis elegans .
Tartarotti B, Sommaruga R, Saul N .Phenotypic and molecular responses of copepods to UV radiation stress in a clear versus a glacially turbid lake.
In 2021:
Dysarz J , Fuellen G, Möller S, Luyten W, Schmitz-Linneweber C , Saul N .Genes implicated in Caenorhabditis elegans and human health regulate stress resistance and physical abilities in aged Caenorhabditis elegans . Möller S, Saul N , Barrantes I, Gézsi A, Walter M, Antal P, Fuellen G.Gene co-expression analyses of health (span) across multiple species. 10.1101/2021.04.08.439030.
Saul N , Möller S, Cirulli F, Berry A, Luyten W, Fuellen G.Health and longevity studies in C. elegans : the “healthy worm database” reveals strengths, weaknesses and gaps of test compound-based studies. 2021 Apr; 22(2), 215-236. doi: 10.1007/s10522-021-09913-2. Sayed S , Siems K, Schmitz-Linneweber C , Luyten W, Saul N .Enhanced Healthspan in Caenorhabditis elegans Treated With Extracts From the Traditional Chinese Medicine Plants Cuscuta chinensis Lam. and Eucommia ulmoides Oliv. . 2021 Feb 02; 12 , 18. doi.org/10.3389/fphar.2021.604435.
In 2020:
Musillo C, Borgi M, Saul N , Möller S, Luyten W, Berry A, Cirulli F.Natural products improve healthspan in aged mice and rats: A systematic review and meta-analysis.
Möller S, Saul N , Cohen AA, Köhling R, Sender S, Escobar HM, Junghanss C, Cirulli F, Berry A, Antal P, Adler P, Vilo J, Boiani M, Jansen L, Repsilber D, Grabe HJ, Struckmann S, Barrantes I, Hamed M, Wouters B, Schoofs L, Luyten W, Fuellen G.Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids.
Di Rosa G, Brunetti G, Scuto M, Trovato Salinaro A, Calabrese EJ, Crea R, Schmitz-Linneweber C , Calabrese V, Saul N .Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson’s Models.
Brunetti G, Di Rosa G, Scuto M, Leri M, Stefani M, Schmitz-Linneweber C , Calabrese V, Saul N .Healthspan Maintenance and Prevention of Parkinson’s-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans .
In 2018:
Fuellen G, Jansen L, Cohen AA, Luyten W, Gogol M, Simm A, Saul N , Cirulli F, Berry A, Antal P, Köhling R, Wouters B, Möller S.Health and Aging: Unifying Concepts, Scores, Biomarkers and Pathways. 2018 Nov 19; 10(4), 883. doi: 10.14336/AD.2018.1030.
Di Rosa G, Saul N , Schmitz-Linneweber C , Calabrese V.Olive oil polyphenols show beneficial effects in two C. elegans Parkinson models.
Tartarotti B, Alfreider A, Egg M, Saul N , Schneider T, Sommaruga R, Tischler A, Vetter J.Seasonal plasticity in photoprotection modulates UV-induced hsp gene expression in copepods from a clear lake. 2018 Feb 16; 63(4), 1579-1592. doi: 10.1002/lno.10793.
In 2016:
Luyten W, Antal P, Braeckman BP, Bundy J, Cirulli F, Fang-Yen C, Fuellen G, Leroi A, Liu Q, Martorell P, Metspalu A, Perola M, Ristow M, Saul N , Schoofs L, Siems K, Temmerman L, Smets T, Wolk A, Rattan SI.Ageing with elegans: a research proposal to map healthspan pathways. Biogerontology. 2016 Aug; 17(4), 771-782. doi: 10.1007/s10522-016-9644-x.
In 2015:
Saul N , Stürzenbaum SR, Chakrabarti S, Baberschke N, Lieke T, Putschew A, Kochan C, Menzel R, Steinberg CEW.Adsorbable organic bromine compounds (AOBr) in aquatic samples: a nematode-based toxicogenomic assessment of the exposure hazard. Environ Sci Pollut Res Int. 2015 Oct; 22(19), 14862-14873. doi: 10.1007/s11356-015-4694-1.Lieke T, Steinberg CEW, Ju J, Saul N. Natural marine and synthetic xenobiotics get on nematode’s nerves: neuro-stimulating and neurotoxic findings in Caenorhabditis elegans . Marine Drugs. 2015 May 06; 13(5), 2785-2812. doi: 10.3390/md13052785.
Baberschke N, Steinberg CEW, Saul N. Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans . Chemosphere. 2015 Apr; 124, 122-128. doi: 10.1016/j.chemosphere.2014.12.002.
In 2014:
Saul N , Chakrabarti S, Stürzenbaum SR, Menzel R, Steinberg CEW.Neurotoxic action of microcystin-LR is reflected in the transcriptional stress response of Caenorhabditis elegans . Chemico-Biological Interactions. 2014 Nov 05; 223, 51-57. doi: 10.1016/j.cbi.2014.09.007. Saul N , Baberschke N, Chakrabarti S, Stürzenbaum SR, Lieke T, Menzel R, Jonáš A, Steinberg CEW.Two organobromines trigger lifespan, growth, reproductive and transcriptional changes in Caenorhabditis elegans . Environ Sci Pollut Res Int. 2014 Sep; 21(17), 10419-10431. doi: 10.1007/s11356-014-2932-6. Ju J, Saul N , Kochan C, Putschew A, Pu Y, Yin L, Steinberg CEW.Cyanobacterial xenobiotics as evaluated by a Caenorhabditis elegans neurotoxicity screening test. Int J Environ Res Public Health. 2014 Apr 25; 11(5), 4589-4606. doi: 10.3390/ijerph110504589.
Ju J, Lieke T, Saul N , Pu Y, Yin L, Kochan C, Putschew A, Baberschke N, Steinberg CEW.Neurotoxic evaluation of two organobromine model compounds and natural AOBr-containing surface water samples by a Caenorhabditis elegans test. Ecotoxicol Environ Saf. 2014 Jun; 104, 194-201. doi: 10.1016/j.ecoenv.2014.03.009.
Tartarotti B, Saul N , Chakrabarti S, Trattner F, Steinberg CEW, Sommaruga R.UV-induced DNA damage in Cyclops abyssorum tatricus populations from clear and turbid alpine lakes. J Plankton Res. 2014 Mar; 36(2), 557-566. doi: 10.1093/plankt/fbt109.
Saul N. Eternal Youth with Tannins? How a Worm Can Outwit Ageing. Atomium Culture (European Institute for Science, Media and Democracy). 2014 Jun 19.
In 2013:
Saul N , Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CEW.Hormesis and longevity with tannins: Free of charge or cost-intensive? Chemosphere. 2013 Oct; 93(6), 1005-1008. doi: 10.1016/j.chemosphere.2013.05.069. Liu S, Saul N , Pan B, Menzel R, Steinberg CEW.The non-target organism Caenorhabditis elegans withstands the impact of sulfamethoxazole. Chemosphere. 2013 Nov; 93(10), 2373-2380. doi: 10.1016/j.chemosphere.2013.08.036.
Steinberg CE, Pietsch K, Saul N , Menzel S, Swain SC, Stürzenbaum SR, Menzel R.Transcript Expression Patterns Illuminate the Mechanistic Background of Hormesis in Caenorhabditis elegans Maupas. Dose Response. 2013 Jan 04; 11, 558-576. doi: 10.2203/dose-response.12-024.Steinberg.
Engert A, Chakrabarti S, Saul N , Bittner M, Menzel R, Steinberg CEW.Interaction of temperature and an environmental stressor: Moina macrocopa responds with increased body size, increased lifespan, and increased offspring numbers slightly above its temperature optimum. Chemosphere. 2013 Feb; 90(7), 2136-2141. doi: 10.1016/j.chemosphere.2012.10.099.
In 2012:
Pietsch K, Saul N , Swain SC, Menzel R, Steinberg CEW, Stürzenbaum SR.Meta-Analysis of Global Transcriptomics Suggests that Conserved Genetic Pathways are Responsible for Quercetin and Tannic Acid Mediated Longevity in C. elegans. Front Genet. 2012 Apr 05; 3, 48. doi: 10.3389/fgene.2012.00048.
Bittner M, Saul N , Steinberg CEW.Antiandrogenic activity of humic substances. Sci Total Environ. 2012 Aug 15; 432, 93-96. doi: 10.1016/j.scitotenv.2012.05.056.
Hofmann S, Timofeyev MA, Putschew A, Saul N , Menzel R, Steinberg CEW.Leaf litter leachates have the potential to increase lifespan, body size, and offspring numbers in a clone of Moina macrocopa . Chemosphere. 2012 Mar; 86(9), 883-890. doi: 10.1016/j.chemosphere.2011.10.041.
In 2011:
Saul N , Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CEW.Diversity of Polyphenol Action in Caenorhabditis elegans : Between Toxicity and Longevity. J Nat Prod. 2011 Aug 26; 74(8), 1713-1720. doi: 10.1021/np200011a. Menzel R, Menzel S, Tiedt S, Kubsch G, Stösser R, Bährs H, Putschew A, Saul N , Steinberg CEW.Enrichment of humic material with hydroxybenzene moieties intensifies its physiological effects on the nematode Caenorhabditis elegans . Environ Sci Technol. 2011 Oct 15; 45(20), 8707-8715. doi: 10.1021/es2023237.
Pietsch K, Saul N , Chakrabarti S, Stürzenbaum SR, Menzel R, Steinberg CEW.Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans . Biogerontology. 2011 Aug; 12(4), 329-347. doi: 10.1007/s10522-011-9334-7.
In 2010:
Saul N , Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW.The longevity effect of tannic acid in Caenorhabditis elegans : Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci. 2010 Jun; 65(6), 626-635. doi: 10.1093/gerona/glq051. Pietsch K, Hofmann S, Henkel R, Saul N , Menzel R, Steinberg CEW.The plant polyphenol caffeic acid affects life traits differently in the nematode Caenorhabditis elegans and the cladoreran Moina macrocopa . Fresenius Environmental Bulletin. 2010 Feb; 19(7), 1238-1244.
In 2009:
Saul N , Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW.Catechin induced longevity in C. elegans : From key regulator genes to disposable soma. Mech Ageing Dev. 2009 Aug; 130(8), 477-486. doi: 10.1016/j.mad.2009.05.005. Pietsch K, Saul N , Menzel R, Stürzenbaum SR, Steinberg CEW.Quercetin mediated lifespan extension in Caenorhabditis e legans is modulated by age-1 , daf-2 , sek-1 and unc-43 . Biogerontology. 2009 Oct; 10(5), 565-578. doi: 10.1007/s10522-008-9199-6.